Key words HFE mutation, HCV infection, iron overload Correspondence
نویسندگان
چکیده
Indeed, when the iron content of liver biopsies from HCV-infected patients was measured, there was only a real increase in hepatic iron in 10% of the cases, despite a rise in serum ferritin and transferrin saturation.8 It should be pointed out that cytolysis could have led to the increase in both serum ferritin and transferrin saturation. In conclusion, it is unlikely that the C282Y mutation of the HFE gene accounts for the iron alterations related to HCV infection. Nevertheless, the role of the H63D mutation in the iron abnormalities warrants further studies.
منابع مشابه
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